SNF8 / EAP30

SNF8, ESCRT-II complex subunit

Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

SNF8 / EAP30 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human SNF8 / EAP30 Protein (Recombinant GST, N-terminus) (aa23-122) - LS-G61809

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SNF8 / EAP30 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69789

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.7 kDa

Price:

20 µg/$1,107

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Human SNF8 / EAP30 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85548

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.7 kDa

Price:

20 µg/$150

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Human SNF8 / EAP30 Protein (Recombinant GST) (Full Length) - LS-G32592

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human SNF8 / EAP30 Protein (Recombinant His) - LS-G1812

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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SNF8 / EAP30 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101001

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.7 kDa

Price:

100 µg/$494

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