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SNAP23 / SNAP-23

synaptosomal-associated protein, 23kDa

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Gene Name: synaptosomal-associated protein, 23kDa
Family/Subfamily: SNAP-25 , Not assigned-Other
Synonyms: SNAP23, HsT17016, SNAP23B, SNAP-23, SNAP23A
Target Sequences: NM_003825 NP_003816.2 O00161

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Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
SNAP23 / SNAP-23 (9)
No (9)
GST (1)
His-T7 (2)
Myc-DDK (Flag) (5)
Human (6)
Mouse (1)
293T Cells (2)
E. coli (3)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
SNAP23 / SNAP-23 Protein - 12.5% SDS-PAGE of human SNAP23 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.95 kDa
10 µg/$479; 25 µg/$670
SNAP23 / SNAP-23 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.6 kDa
100 µg/$494
SNAP23 / SNAP-23 Protein - Recombinant  Synaptosomal Associated Protein 23kDa By SDS-PAGE
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E. coli
His-T7
27.1 kDa
10 µg/$274; 50 µg/$400; 100 µg/$637; 200 µg/$797; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053
SNAP23 / SNAP-23 Protein - Recombinant  Synaptosomal Associated Protein 23kDa By SDS-PAGE
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E. coli
His-T7
27.1 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
SNAP23 / SNAP-23 Protein - Purified recombinant protein SNAP23 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$150
SNAP23 / SNAP-23 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.6 kDa
20 µg/$150
SNAP23 / SNAP-23 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
100 µg/$494
SNAP23 / SNAP-23 Protein
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E. coli
None
50 µg/$361; 250 µg/$739; 10 µg/$261
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).