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SMYD3

SET and MYND domain containing 3

Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.

Gene Name:	SET and MYND domain containing 3
Synonyms:	SMYD3, BA74P14.1, BA74P14.1 (novel protein), KMT3E, ZMYND1, ZNFN3A1
Target Sequences:	NM_022743 NP_073580.1 Q9H7B4

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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