SMUG1

single-strand-selective monofunctional uracil-DNA glycosylase 1

Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. The activity is greater against mismatches (U/G) than against matches (U/A). Excised uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine) and other oxidized damage. The activity is damage specificity and salt concentration-dependent. The general order of the preference for ssDNA and dsDNA is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at the low salt concentration. At the high concentration dsDNA (G pair) > dsDNA (A pair) > ssDNA.

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Products

Antibodies (39)

Type

Primary (39)

Target

SMUG1 (39)

Reactivity

Human (39)

Mouse (14)

Rat (14)

Bat (3)

Chimpanzee (3)

Gibbon (3)

Horse (3)

Monkey (6)

Pig (3)

Application

IHC (5)

IHC-P (1)

WB (33)

ELISA (15)

ICC (2)

IF (2)

Peptide-ELISA (2)

Host

rabbit (34)

mouse (4)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (22)

IgG2a (4)

Clonality

monoclonal mc (4)

polyclonal pc (35)

Clone

OTI5G1 (2)

OTI6B3 (2)

Format

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Carrier-free (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (21)

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Epitope

aa1-270 (8)

aa43-71 (7)

aa110-159 (4)

60-140 aa, Internal (1)

Internal (1)

aa137-182 (1)

aa2-14 (1)

Publications

No (39)

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IHC-plus™ SMUG1 Antibody (aa2-14) LS-B2587

(4.0) Rating

Antibody:

SMUG1 Goat anti-Human Polyclonal (aa2-14) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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SMUG1 Antibody (aa137-182) LS-C313788

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa137-182) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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SMUG1 Antibody (Internal) LS-C353362

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$299

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SMUG1 Antibody LS-C805551

Antibody:

SMUG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SMUG1 Antibody (60-140 aa, Internal) LS-C386115

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SMUG1 Antibody LS-C830681

Antibody:

SMUG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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SMUG1 Antibody LS-C832188

Antibody:

SMUG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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SMUG1 Antibody (aa43-71) LS-C325216

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa43-71) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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SMUG1 Antibody (aa43-71, Biotin) LS-C207671

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa43-71) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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SMUG1 Antibody (aa43-71, FITC) LS-C207672

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa43-71) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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SMUG1 Antibody (aa43-71, APC) LS-C207670

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa43-71) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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SMUG1 Antibody (aa43-71, Azide-free, HRP) LS-C207673

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa43-71) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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SMUG1 Antibody (aa43-71, PE) LS-C207674

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa43-71) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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SMUG1 Antibody LS-C742756

Antibody:

SMUG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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SMUG1 Antibody LS-C827021

Antibody:

SMUG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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SMUG1 Antibody (clone OTI5G1) LS-C795411

Antibody:

SMUG1 Mouse anti-Human Monoclonal (OTI5G1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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SMUG1 Antibody (clone OTI5G1, Carrier-free) LS-C798778

Antibody:

SMUG1 Mouse anti-Human Monoclonal (Carrier-free) (OTI5G1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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SMUG1 Antibody (clone OTI6B3) LS-C795421

Antibody:

SMUG1 Mouse anti-Human Monoclonal (OTI6B3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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SMUG1 Antibody (clone OTI6B3, Carrier-free) LS-C792449

Antibody:

SMUG1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6B3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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SMUG1 Antibody LS-C377701

Antibody:

SMUG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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SMUG1 Antibody (HRP) LS-C377705

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

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SMUG1 Antibody (aa110-159) LS-C81981

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa110-159) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SMUG1 Antibody (aa43-71) LS-C159045

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa43-71) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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SMUG1 Antibody LS-C357085

Antibody:

SMUG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

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SMUG1 Antibody (aa1-270) LS-C373556

Antibody:

SMUG1 Rabbit anti-Human Polyclonal (aa1-270) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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