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SMS2 / SGMS2

sphingomyelin synthase 2

Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.

Gene Name: sphingomyelin synthase 2
Synonyms: SGMS2, SM synthase, Sphingomyelin synthase 2, SMS2
Target Sequences: NM_152621 Q8NHU3 Q8NHU3

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Products
Proteins (8)
Over-Expression Lysate (6)
Recombinant (2)
SMS2 / SGMS2 (8)
No (8)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (5)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.1 kDa
100 µg/$494
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.1 kDa
100 µg/$494
SMS2 / SGMS2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.1 kDa
100 µg/$494
SMS2 / SGMS2 Protein - 12.5% SDS-PAGE of human MGC26963 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.7 kDa
2 µg/$439
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.1 kDa
20 µg/$150
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.1 kDa
20 µg/$150
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.1 kDa
20 µg/$150
Viewing 1-8 of 8 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).