Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
Gene Name: | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) |
Synonyms: | SMPD3, Neutral sphingomyelinase 2, NSMase-2, Neutral sphingomyelinase II, NSMASE2 |
Target Sequences: | NM_018667 NP_061137.1 Q9NY59 |
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