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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SMPD1 / Acid Sphingomyelinase

sphingomyelin phosphodiesterase 1, acid lysosomal

Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.

Gene Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Family/Subfamily: Phosphodiesterase - Other , not assigned-Phosphodiesterase - Other
Synonyms: SMPD1, Acid sphingomyelinase, ASM, NPD, ASMASE
Target Sequences: NM_000543 NP_000534.3 P17405

Filtered by: None
Type
Over-Expression Lysate (4)
Recombinant (8)
Target
SMPD1 / Acid Sphingomyelinase (12)
Tag
GST (1)
GST,N-terminus (1)
His (4)
His + T7 (1)
Myc + DDK (5)
Species
Human (9)
Mouse (1)
Source
293T Cells (2)
Baculovirus (4)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purification
Purified (6)
Low Endotoxin Level
Low endotoxin level (4)
Publications
No (12)
Showing 1-12 of 12 results

Human SMPD1 / Acid Sphingomyelinase Protein (Recombinant His + T7) (aa319-579) - LS-G13689
E. coli
His + T7
33.9 kDa
10µg  $275.00; 50µg  $445.00; 100µg  $575.00; 200µg  $845.00; 1mg  $2,160.00
Recombinant Acid Sphingomyelinase By SDS-PAGE

Human SMPD1 / Acid Sphingomyelinase Protein (Recombinant Myc + DDK) (Full Length) - LS-G67013
HEK 293 Cells
Myc + DDK
65 kDa
20µg  $890.00
Purified recombinant protein SMPD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human SMPD1 / Acid Sphingomyelinase Protein (Recombinant GST) (Full Length) - LS-G30466
Wheat Germ Extract
GST
65.78 kDa
2µg  $385.00
12.5% SDS-PAGE of human SMPD1 stained with Coomassie Blue

Human SMPD1 / Acid Sphingomyelinase Protein (Recombinant His) (Gly85-Cys631) - LS-G98664
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
65 kDa
10µg  $485.00; 20µg  $815.00

Human SMPD1 / Acid Sphingomyelinase Protein (Recombinant His) (Met1-Cys631) - LS-G98663
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
65 kDa
10µg  $650.00; 20µg  $980.00

Human SMPD1 / Acid Sphingomyelinase Protein (Recombinant His) (Met1-Pro628) - LS-G97899
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
66.3 kDa
10µg  $485.00; 50µg  $1,215.00

Human SMPD1 / Acid Sphingomyelinase Protein (Recombinant GST,N-terminus) (aa531-630) - LS-G60151
Wheat Germ Extract
GST,N-terminus
2µg  $385.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Mouse SMPD1 / Acid Sphingomyelinase Protein (Recombinant His) (Met1-Leu626) - LS-G98849
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
66.3 kDa
10µg  $485.00; 20µg  $815.00

SMPD1 / Acid Sphingomyelinase Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G99075
HEK 293 Cells
Myc + DDK
69.94 kDa
100µg  $485.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

SMPD1 / Acid Sphingomyelinase Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G122015
HEK 293 Cells
Myc + DDK
69.81 kDa
100µg  $485.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human SMPD1 / Acid Sphingomyelinase Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G78932
293T Cells
Myc + DDK
69.94 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human SMPD1 / Acid Sphingomyelinase Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G78933
293T Cells
Myc + DDK
69.81 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Showing 1-12 of 12 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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