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SMPD1 / Acid Sphingomyelinase

sphingomyelin phosphodiesterase 1, acid lysosomal

Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.

Gene Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Family/Subfamily: Phosphodiesterase - Other , not assigned-Phosphodiesterase - Other
Synonyms: SMPD1, Acid sphingomyelinase, ASM, NPD, ASMASE
Target Sequences: NM_000543 NP_000534.3 P17405

Publications (3)

1
Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes. Shamroop Kumar Mallela, Alla Mitrofanova, Sandra Merscher, Alessia Fornoni. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2019 December;1864:158517. [Full Text Article] [PubMed:31487557] [PMC:PMC6832884] Related Antibodies: LS-C334919.
2
Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases. Yue-Hong Chen, Rong-Han Liu, Ya-Zhou Cui, Aubryanna Hettinghouse, Wen-Yu Fu, Lei Zhang, Chen Zhang, Chuan-Ju Liu. Arthritis research & therapy. 2022 January;24:27. [Full Text Article] [PubMed:35045889] [PMC:PMC8767691] Related Antibodies: LS-C334919.
3
Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation During Hypercholesterolemia. Xinxu Yuan, Owais M Bhat, Yao Zou, Xiang Li, Yang Zhang, Pin-Lan Li. Journal of lipid research. 2022 October;63:100298. [Full Text Article] [PubMed:36252682] [PMC:PMC9672920] Related Antibodies: LS-C334919.

☰ Filters
Products
ELISA Kits (22)
Competitive EIA (1)
Custom (1)
Sandwich (19)
Sandwich CLIA (1)
SMPD1 / Acid Sphingomyelinase (22)
Human (9)
Mouse (1)
Rat (1)
Chicken (2)
Monkey (2)
Porcine (2)
Rabbit (2)
Sheep (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (18)
No (22)
Cell Culture Supernatants (3)
Cerebrospinal Fluid (1)
Heparin Plasma (1)
Plasma (10)
Serum (11)
Tissue Homogenates (2)
Urine (1)
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Microplate
Human
1.22 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cerebrospinal Fluid, Plasma, Serum, Urine
1 Plate/$1,041
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
78.125 - 5000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
SMPD1 / Acid Sphingomyelinase ELISA Kit
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Sandwich
Human
15.6 - 1000 pg/ml
Cell Culture Supernatants, Heparin Plasma, Serum
1 Plate/$795
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SMPD1 / Acid Sphingomyelinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).