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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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SMOC2
SPARC related modular calcium binding 2
SMOC2 is a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants.
| Gene Name: | SPARC related modular calcium binding 2 |
| Synonyms: | SMOC2, BA270C4A.1, BA37D8.1, DTDP1, MST117, MSTP117, RP11-270C4__A.1, SMAP-2, DJ421D16.1, MSTP140, SMOC-2 |
| Target Sequences: | NM_022138 NP_071421.1 Q9H3U7 |
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