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SMIF / DCP1A

decapping mRNA 1A

Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.

Gene Name:	decapping mRNA 1A
Synonyms:	DCP1A, Decapping enzyme hDcp1a, Nbla00360, HSA275986, Transcription factor SMIF, MRNA-decapping enzyme 1A, SMIF, SMAD4IP1
Target Sequences:	NM_018403

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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