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Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8.
Gene Name: | SMG9 nonsense mediated mRNA decay factor |
Synonyms: | SMG9, C19orf61, F17127_1, Protein smg-9 homolog, Protein SMG9 |
Target Sequences: | NM_019108 NP_061981.2 Q9H0W8 |
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