SMG7

SMG7 nonsense mediated mRNA decay factor

SMG7 is a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Products

Antibodies (15)

Proteins (2)

ELISA Kits (1)

Type

Cell-Based (1)

Over-Expression Lysate (2)

Primary (15)

Target

SMG7 (18)

Reactivity

Human (16)

Mouse (3)

Rat (2)

Application

IHC (5)

IHC-P (3)

WB (11)

ELISA (6)

ICC (1)

IF (6)

IP (2)

Peptide-ELISA (2)

Host

rabbit (15)

Isotype

IgG (12)

Clonality

polyclonal pc (15)

Format

96-Well Microplate (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (12)

Epitope

490-570 aa, Internal (1)

Internal (1)

Lys548 (1)

aa1087-1137 (1)

aa521-570 (1)

aa896-930 (1)

Publications

No (18)

Sample Type

Adherent Cell Cultures (1)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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SMG7 Antibody (Internal) LS-C353204

Antibody:

SMG7 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$299

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SMG7 Antibody LS-C681404

Antibody:

SMG7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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SMG7 Antibody (HRP) LS-C681405

Antibody:

SMG7 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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SMG7 Antibody (Biotin) LS-C681406

Antibody:

SMG7 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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SMG7 Antibody (FITC) LS-C681403

Antibody:

SMG7 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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SMG7 Antibody (490-570 aa, Internal) LS-C386102

Antibody:

SMG7 Rabbit anti-Human Polyclonal (490-570 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SMG7 Antibody LS-C823111

Antibody:

SMG7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

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SMG7 Antibody (aa521-570) LS-C119181

Antibody:

SMG7 Rabbit anti-Human Polyclonal (aa521-570) Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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SMG7 Antibody LS-C804577

Antibody:

SMG7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SMG7 Antibody LS-C155648

Antibody:

SMG7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

SMG7 Antibody (Lys548) LS-C191987

Antibody:

SMG7 Rabbit anti-Human Polyclonal (Lys548) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

SMG7 Antibody (aa1087-1137) LS-C288924

Antibody:

SMG7 Rabbit anti-Human Polyclonal (aa1087-1137) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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SMG7 Antibody LS-C770738

Antibody:

SMG7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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SMG7 Antibody (aa896-930) LS-C344489

Antibody:

SMG7 Rabbit anti-Human Polyclonal (aa896-930) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

SMG7 Antibody LS-C750342

Antibody:

SMG7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SMG7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130391

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

128.3 kDa

Price:

100 µg/$710

Select

Human SMG7 (Cell-Based ELISA) ELISA Kit - LS-F3269

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

Select

Human SMG7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76702

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

128.3 kDa

Price:

20 µg/$215

Viewing 1-18 of 18 product results

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