SMC6

structural maintenance of chromosomes 6

Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies.

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Antibodies (8)

Type

Primary (8)

Target

SMC6 (8)

Reactivity

Human (8)

Mouse (3)

Rat (3)

Bovine (3)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (3)

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Application

IHC (1)

WB (7)

ELISA (3)

Host

rabbit (7)

mouse (1)

Isotype

IgG (2)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (7)

Clone

2E6 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (5)

Epitope

C-Terminus (4)

aa1050-C-term (1)

Publications

No (8)

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SMC6 Antibody (clone 2E6) LS-C133814

Antibody:

SMC6 Mouse anti-Human Monoclonal (2E6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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SMC6 Antibody LS-C662723

Antibody:

SMC6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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SMC6 Antibody LS-C754261

Antibody:

SMC6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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SMC6 Antibody (aa1050-C-term) LS-C286446

Antibody:

SMC6 Rabbit anti-Human Polyclonal (aa1050-C-term) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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SMC6 Antibody (C-Terminus) LS-C151617

Antibody:

SMC6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SMC6 Antibody (C-Terminus, HRP) LS-C471708

Antibody:

SMC6 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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SMC6 Antibody (C-Terminus, Biotin) LS-C471705

Antibody:

SMC6 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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SMC6 Antibody (C-Terminus, FITC) LS-C471706

Antibody:

SMC6 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

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