SMC5

structural maintenance of chromosomes 5

Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; the function seems to be independent of SMC6.

☰ Filters

Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

SMC5 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Select

SMC5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113463

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

128.6 kDa

Price:

100 µg/$494

Select

Human SMC5 Protein (Recombinant GST, N-terminus) (aa992-1101) - LS-G61925

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human SMC5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79967

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

128.6 kDa

Price:

20 µg/$150

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.