SMC5

structural maintenance of chromosomes 5

Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; the function seems to be independent of SMC6.

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Products

Antibodies (9)

Type

Primary (9)

Target

SMC5 (9)

Reactivity

Human (9)

Mouse (3)

Rat (2)

Monkey (1)

Application

WB (5)

ELISA (2)

IP (1)

Peptide-ELISA (2)

Host

rabbit (8)

goat (1)

Isotype

IgG (8)

Clonality

polyclonal pc (9)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (6)

Epitope

aa1050-C-term (1)

aa679-692 (1)

Publications

No (9)

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SMC5 Antibody LS-C671496

Antibody:

SMC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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SMC5 Antibody (HRP) LS-C671498

Antibody:

SMC5 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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SMC5 Antibody (Biotin) LS-C671499

Antibody:

SMC5 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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SMC5 Antibody (FITC) LS-C671500

Antibody:

SMC5 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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SMC5 Antibody LS-C332049

Antibody:

SMC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SMC5 Antibody LS-C752975

Antibody:

SMC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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SMC5 Antibody LS-C803944

Antibody:

SMC5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SMC5 Antibody (aa1050-C-term) LS-C287150

Antibody:

SMC5 Rabbit anti-Human Polyclonal (aa1050-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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SMC5 Antibody (aa679-692) LS-C108899

Antibody:

SMC5 Goat anti-Human Polyclonal (aa679-692) Antibody

Reactivity:

Human, Monkey

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

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