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SMC1B

structural maintenance of chromosomes 1B

Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.

Gene Name: structural maintenance of chromosomes 1B
Synonyms: SMC1B, BK268H5.5, SMC1L2, SMC protein 1B, SMC-1-beta, SMC-1B, SMC1BETA, BK268H5
Target Sequences: NM_148674 NP_683515.4 Q8NDV3

☰ Filters
Antibodies (16)
Proteins (3)
Over-Expression Lysate (2)
Primary (16)
Recombinant (1)
SMC1B (19)
Human (16)
Rat (2)
IHC (9)
IHC-P (3)
WB (12)
ELISA (11)
ICC (1)
IF (1)
Peptide-ELISA (1)
rabbit (16)
IgG (14)
polyclonal pc (16)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (8)
aa737-765 (7)
aa154-433 (1)
No (19)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
SMC1B Antibody - IHC of paraffin-embedded SAS xenograft using SMC1B antibody at 1:500 dilution.
Select
SMC1B Rabbit anti-Human Polyclonal (aa154-433) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
SMC1B Antibody - SMC1B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human colon tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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SMC1B Rabbit anti-Human Polyclonal (aa737-765) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
SMC1B Rabbit anti-Human Polyclonal (aa737-765) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
SMC1B Rabbit anti-Human Polyclonal (aa737-765) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
SMC1B Rabbit anti-Human Polyclonal (aa737-765) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
SMC1B Rabbit anti-Human Polyclonal (aa737-765) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
SMC1B Rabbit anti-Human Polyclonal (aa737-765) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
SMC1B Rabbit anti-Human Polyclonal (aa737-765) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SMC1B Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SMC1B Antibody - Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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SMC1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
SMC1B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
SMC1B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
SMC1B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
SMC1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
SMC1B Antibody - Western blot analysis of extracts of rat testis, using SMC1B antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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SMC1B Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SMC1B Antibody - Western blot analysis of extracts of rat testis using SMC1B Polyclonal Antibody at dilution of 1:3000.
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SMC1B Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SMC1B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SMC1B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
143.7 kDa
20 µg/$215
SMC1B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
143.7 kDa
100 µg/$710
Viewing 1-19 of 19 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).