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SMAD5

SMAD family member 5

SMAD5 is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

Gene Name: SMAD family member 5
Synonyms: SMAD5, JV5-1, MADH5, SMAD 5, MAD homolog 5, Mothers against DPP homolog 5, SMA- and MAD-related protein 5, SMAD family member 5, DWFC, HSmad5
Target Sequences: NM_005903 NP_005894.3 Q99717

Publications (1)

1
Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells. Yu PB, Deng DY, Beppu H, Hong CC, Lai C, Hoyng SA, Kawai N, Bloch KD. The Journal of biological chemistry. 2008 283:3877-88. (WB, IP) [PubMed:18042551]

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Products
Proteins (12)
Over-Expression Lysate (6)
Recombinant (6)
SMAD5 (12)
No (12)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (6)
Human (7)
Mouse (2)
293T Cells (3)
Baculovirus (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
SMAD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.1 kDa
100 µg/$710
SMAD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.1 kDa
100 µg/$710
SMAD5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SMAD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.1 kDa
100 µg/$494
SMAD5 Protein
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E. coli
His, N-Terminal
52.1 kDa
50 µg/$419
SMAD5 Protein - 12.5% SDS-PAGE of human SMAD5 stained with Coomassie Blue
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Wheat Germ Extract
GST
78.7 kDa
2 µg/$439
SMAD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
52.1 kDa
20 µg/$215
SMAD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
52.1 kDa
20 µg/$215
SMAD5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
52.1 kDa
20 µg/$150
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Baculovirus
None
Less than 1.0 EU/µg protein (determined by LAL method).
52.2 kDa
100 µg/$843
SMAD5 Protein - Recombinant Mothers Against Decapentaplegic Homolog 5 By SDS-PAGE
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E. coli
His-T7
32.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
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Baculovirus
His-GST
Less than 1.0 EU/µg protein (determined by LAL method).
79.9 kDa
100 µg/$843
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).