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Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).
Gene Name: | SLIT and NTRK-like family, member 5 |
Synonyms: | SLITRK5, BA364G4.2, LRRC11, Slit and trk like gene 5, SLIT and NTRK-like protein 5, KIAA0918 |
Target Sequences: | AB020725 BAA74941.1 O94991 |
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