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SLC9A3 / NHE3

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.

Gene Name: solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Family/Subfamily: Transporter , Monovalent cation:proton antiporter-1
Synonyms: SLC9A3, Na+/H+ exchanger 3, NHE3, Sodium/hydrogen exchanger 3, Na(+)/H(+) exchanger 3, NHE-3
Target Sequences: NM_004174 NP_004165.2 P48764

Publications (10)

1
Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney. Biemesderfer D, Rutherford PA, Nagy T, Pizzonia JH, Abu-Alfa AK, Aronson PS. The American journal of physiology. 1997 273:F289-99. [PubMed:9277590]
2
Membrane topology of NHE3. Epitopes within the carboxyl-terminal hydrophilic domain are exoplasmic. Biemesderfer D, DeGray B, Aronson PS. The Journal of biological chemistry. 1998 273:12391-6. [PubMed:9575193]
3
In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition. Zhang Y, Norian JM, Magyar CE, Holstein-Rathlou NH, Mircheff AK, McDonough AA. The American journal of physiology. 1999 276:F711-9. [PubMed:10330053]
4
Specific association of megalin and the Na+/H+ exchanger isoform NHE3 in the proximal tubule. Biemesderfer D, Nagy T, DeGray B, Aronson PS. The Journal of biological chemistry. 1999 274:17518-24. [PubMed:10364184]
5
Chronic effect of parathyroid hormone on NHE3 expression in rat renal proximal tubules. Girardi AC, Titan SM, Malnic G, Rebouas NA. Kidney international. 2000 58:1623-31. [PubMed:11012896]
6
Na+/H+-exchange activity and immunolocalization of NHE3 in rat epididymis. Bagnis C, Marsolais M, Biemesderfer D, Laprade R, Breton S. American journal of physiology. Renal physiology. 2001 280:F426-36. [PubMed:11181404]
7
Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na+/H+ exchanger NHE3 at PKA consensus sites. Kocinsky HS, Girardi AC, Biemesderfer D, Nguyen T, Mentone S, Orlowski J, Aronson PS. American journal of physiology. Renal physiology. 2005 289:F249-58. (ICC, IHC, WB, ELISA) [PubMed:15687252]
8
NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity. Kocinsky HS, Dynia DW, Wang T, Aronson PS. American journal of physiology. Renal physiology. 2007 293:F212-8. [PubMed:17409282]
9
NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase. Dynia DW, Steinmetz AG, Kocinsky HS. American journal of physiology. Renal physiology. 2010 298:F745-53. [PubMed:20015946] [PMC:PMC2838583]
10
Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice. Rieg T, Gerasimova M, Murray F, Masuda T, Tang T, Rose M, Drucker DJ, Vallon V. American journal of physiology. Renal physiology. 2012 303:F963-71. (WB; Mouse) [PubMed:22832924] [PMC:PMC3469689]
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☰ Filters
Antibodies (37)
ELISA Kits (1)
Proteins (1)
Primary (37)
Recombinant (1)
Sandwich (1)
SLC9A3 / NHE3 (39)
Human (13)
Mouse (24)
Rat (34)
Chimpanzee (3)
Gibbon (3)
Monkey (3)
Opossum (10)
Primate (2)
Rabbit (16)
IHC (13)
IHC-P (1)
WB (37)
ELISA (8)
ICC (22)
IF (10)
IP (16)
Peptide-ELISA (1)
rabbit (19)
mouse (16)
rabbit-new zealand white (2)
IgG (4)
IgG1 (6)
IgG2a (1)
IgG2b (5)
monoclonal mc (16)
polyclonal pc (21)
10A8 (5)
14D5 (5)
96-Well Strip Plate (1)
AP Conjugated (1)
APC Conjugated (2)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 594 Conjugated (1)
Biotin Conjugated (5)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (2)
PE Conjugated (1)
PerCP Conjugated (1)
RPE Conjugated (1)
Unconjugated (12)
pSer552 (5)
pSer605 (5)
C-Terminus (4)
aa611-660 (4)
aa300-350 (1)
aa450-500 (1)
No (39)
Cell Lysates (1)
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Human (1)
Wheat Germ Extract (1)
SLC9A3 / NHE3 Antibody - Sodium / Hydrogen Exchanger 3 [phospho Ser552] Antibody (14D5) - Detection of NHE3 [S552] in human kidney lysate..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer552) (14D5) Antibody
Rabbit, Mouse, Rat, Opossum, Human
ELISA, IF, IHC, IP, WB
Unconjugated
0.1 ml/$386
SLC9A3 / NHE3 Antibody - Sodium / Hydrogen Exchanger 3 [phospho Ser552] Antibody (14D5) - Detection of NHE3 [S552] in human kidney lysate..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer552) (Biotin) (14D5) Antibody
Rabbit, Mouse, Rat, Opossum, Primate, Human
ELISA, IF, IHC, IP, WB
Biotin Conjugated
0.1 ml/$416
SLC9A3 / NHE3 Antibody - Sodium / Hydrogen Exchanger 3 [phospho Ser552] Antibody (14D5) - Detection of NHE3 [S552] in human kidney lysate..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer552) (DY550) (14D5) Antibody
Rabbit, Mouse, Rat, Opossum, Human
ELISA, IF, IHC, IP, WB
DY550 Conjugated
0.1 ml/$416
SLC9A3 / NHE3 Antibody - Sodium / Hydrogen Exchanger 3 [phospho Ser552] Antibody (14D5) - Detection of NHE3 [S552] in human kidney lysate..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer552) (DY488) (14D5) Antibody
Rabbit, Mouse, Rat, Opossum, Human
ELISA, IF, IHC, IP, WB
DY488 Conjugated
0.1 ml/$416
SLC9A3 / NHE3 Antibody - Sodium / Hydrogen Exchanger 3 [phospho Ser552] Antibody (14D5) - Detection of NHE3 [S552] in human kidney lysate..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer552) (DY650) (14D5) Antibody
Rabbit, Mouse, Rat, Opossum, Human
ELISA, IF, IHC, IP, WB
DY650 Conjugated
0.1 ml/$416
SLC9A3 / NHE3 Antibody - Western blot analysis of NHE3 in rat kidney tissues using a 1:1000 dilution of SLC9A3 / NHE3 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A3 / NHE3 Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat
ICC, WB
Unconjugated
100 µg/$449
SLC9A3 / NHE3 Antibody - Western blot analysis of NHE3 in rat kidney tissues using a 1:1000 dilution of SLC9A3 / NHE3 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC9A3 / NHE3 Rabbit anti-Rat Polyclonal (Atto 594) Antibody
Mouse, Rat
ICC, WB
Atto 594 Conjugated
100 µg/$486
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SLC9A3 / NHE3 Mouse anti-Rabbit Monoclonal (C-Terminus) Antibody
Rabbit, Rat
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$748
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SLC9A3 / NHE3 Mouse anti-Rabbit Monoclonal (HRP) Antibody
Rabbit, Rat
ICC, IHC, IP, WB
HRP Conjugated
100 µl/$990
Select
SLC9A3 / NHE3 Mouse anti-Rabbit Monoclonal (Biotin) Antibody
Rabbit, Rat
ICC, IHC, IP, WB
Biotin Conjugated
100 µl/$990
Select
SLC9A3 / NHE3 Mouse anti-Rabbit Monoclonal (FITC) Antibody
Rabbit, Rat
ICC, IHC, IP, WB
FITC Conjugated
100 µl/$990
Select
SLC9A3 / NHE3 Mouse anti-Rabbit Monoclonal (APC) Antibody
Rabbit, Rat
ICC, IHC, IP, WB
APC Conjugated
100 µl/$990
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SLC9A3 / NHE3 Mouse anti-Rabbit Monoclonal (PE) Antibody
Rabbit, Rat
ICC, IHC, IP, WB
PE Conjugated
100 µl/$990
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SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer605) (10A8) Antibody
Rabbit, Mouse, Rat, Opossum
ICC, IF, IP, WB
Unconjugated
0.1 ml/$386
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer605) (Biotin) (10A8) Antibody
Rabbit, Mouse, Rat, Opossum, Primate
ICC, IF, IP, WB
Biotin Conjugated
0.1 ml/$416
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer605) (DY488) (10A8) Antibody
Rabbit, Mouse, Rat, Opossum
ICC, IF, IP, WB
DY488 Conjugated
0.1 ml/$416
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer605) (DY650) (10A8) Antibody
Rabbit, Mouse, Rat, Opossum
ICC, IF, IP, WB
DY650 Conjugated
0.1 ml/$416
Select
SLC9A3 / NHE3 Mouse anti-Rat Monoclonal (pSer605) (DY550) (10A8) Antibody
Rabbit, Mouse, Rat, Opossum
ICC, IF, IP, WB
DY550 Conjugated
0.1 ml/$416
Select
SLC9A3 / NHE3 Rabbit-New Zealand White anti-Human Polyclonal (aa450-500) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$393
Select
SLC9A3 / NHE3 Rabbit-New Zealand White anti-Human Polyclonal (aa300-350) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$393
Select
SLC9A3 / NHE3 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
SLC9A3 / NHE3 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat
ICC, WB
Unconjugated
100 µl/$632
SLC9A3 / NHE3 Antibody - Western blot analysis SLC9A3 using COLO205 whole cells lysates
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SLC9A3 / NHE3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
SLC9A3 / NHE3 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
100 µg/$832
Select
SLC9A3 / NHE3 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$860
Viewing 1-25 of 39 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).