SLC8B1 / SLC24A6 / NCLX

solute carrier family 8 (sodium/lithium/calcium exchanger), member B1

Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis. Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Able to transport Ca2+ in exchange of either Li+ or Na+, explaining how Li+ catalyzes Ca2+ exchange. In contrast to other members of the family its function is independent of K+.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

SLC8B1 / SLC24A6 / NCLX (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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SLC8B1 / SLC24A6 / NCLX Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109647

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.1 kDa

Price:

100 µg/$494

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Human SLC8B1 / SLC24A6 / NCLX Protein (Recombinant GST) (Full Length) - LS-G35362

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

90.6 kDa

Price:

2 µg/$439

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Human SLC8B1 / SLC24A6 / NCLX Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91874

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.1 kDa

Price:

20 µg/$150

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