SLC8A1 / NCX1

solute carrier family 8 (sodium/calcium exchanger), member 1

In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.

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Products

ELISA Kits (6)

Type

Custom (4)

Sandwich (2)

Target

SLC8A1 / NCX1 (6)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Dog (1)

Format

96-Well Strip Plate (6)

Publications

No (6)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (2)

Serum (1)

Tissue Homogenates (2)

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Human SLC8A1 / NCX1 (Sandwich ELISA) ELISA Kit - LS-F14280

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Tissue Homogenates

Price:

1 Plate/$783

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Rat SLC8A1 / NCX1 (Custom ELISA) ELISA Kit - LS-F14279

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine SLC8A1 / NCX1 (Custom ELISA) ELISA Kit - LS-F14281

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse SLC8A1 / NCX1 (Custom ELISA) ELISA Kit - LS-F14283

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Dog SLC8A1 / NCX1 (Custom ELISA) ELISA Kit - LS-F14282

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Human SLC8A1 / NCX1 (Sandwich ELISA) ELISA Kit - LS-F33386

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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