SLC7A8 / LAT2

solute carrier family 7 (amino acid transporter light chain, L system), member 8

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

SLC7A8 / LAT2 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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SLC7A8 / LAT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104165

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37 kDa

Price:

100 µg/$494

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Human SLC7A8 / LAT2 Protein (Recombinant GST) (Full Length) - LS-G32840

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.8 kDa

Price:

2 µg/$439

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Human SLC7A8 / LAT2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69032

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

20 µg/$1,107

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Human SLC7A8 / LAT2 Protein (Recombinant GST, N-terminus) (aa467-535) - LS-G61993

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SLC7A8 / LAT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83462

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.2 kDa

Price:

20 µg/$150

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Human SLC7A8 / LAT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83463

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37 kDa

Price:

20 µg/$150

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SLC7A8 / LAT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101061

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.2 kDa

Price:

100 µg/$494

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