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SLC6A3 / Dopamine Transporter

solute carrier family 6 (neurotransmitter transporter), member 3

SLC6A3 / Dopamine Transporter is a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.

Gene Name: solute carrier family 6 (neurotransmitter transporter), member 3
Family/Subfamily: Transporter , Neurotransmitter:sodium symporter
Synonyms: SLC6A3, DA transporter, DAT1, DAT
Target Sequences: NM_001044 NP_001035.1 Q01959

Publications (2)

1
Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. Michela Di Salvio, Luca Giovanni Di Giovannantonio, Dario Acampora, Raffaele Prosperi, Daniela Omodei, Nilima Prakash, Wolfgang Wurst, Antonio Simeone. Nature neuroscience. 2010 December;13:1481-8. [Full Text Article] [PubMed:21057506]
2
Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma. Schrödter S, Braun M, Syring I, Klümper N, Deng M, Schmidt D, Perner S, Müller SC, Ellinger J. Molecular cancer. 2016 15:10. (WB; Human) [Full Text Article] [PubMed:26831905] [PMC:PMC4736613] Related Antibodies: LS-B7715.

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Antibodies (51)
Primary (51)
SLC6A3 / Dopamine Transporter (51)
Human (35)
Mouse (18)
Rat (27)
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SLC6A3 / Dopamine Transporter Antibody - Anti-SLC6A3 / Dopamine Transporter antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
SLC6A3 / Dopamine Transporter Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SLC6A3 / Dopamine Transporter Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SLC6A3 / Dopamine Transporter Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SLC6A3 / Dopamine Transporter Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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SLC6A3 / Dopamine Transporter Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Dog, Rat, Human
ELISA, WB
Unconjugated
100 µl/$801
SLC6A3 / Dopamine Transporter Antibody - Western blot of human caudate lysate showing specific immunolabeling of the ~88k DAT protein.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$469
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SLC6A3 / Dopamine Transporter Rat anti-Human Monoclonal (N-Terminus) Antibody
Mouse, Rat, Human, Monkey
ICC, IHC, WB
Unconjugated
100 µl/$832
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Human, Monkey
IHC, IHC-Fr, WB
Unconjugated
100 µl/$860
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SLC6A3 / Dopamine Transporter Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
SLC6A3 / Dopamine Transporter Antibody - Immunohistochemistry-Paraffin: DAT1 Antibody (mAb16) - IHC analysis of DAT1 in mouse brain using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC6A3 / Dopamine Transporter Mouse anti-Rat Monoclonal (N-Terminus) (mAb16) Antibody
Mouse, Rat
ELISA, ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$386
SLC6A3 / Dopamine Transporter Antibody - Immunofluorescent analysis of HepG2 cells using SLC6A3 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
SLC6A3 / Dopamine Transporter Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
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SLC6A3 / Dopamine Transporter Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Rat
ELISA, IHC, IHC-Fr, IP, WB
Unconjugated
50 µg/$826
SLC6A3 / Dopamine Transporter Antibody - Immunohistochemistry of paraffin-embedded Rat brain using SLC6A3 Polyclonal Antibody at dilution of 1:200 (40x lens).
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
SLC6A3 / Dopamine Transporter Antibody - Confocal immunofluorescence imaging of dopamine transporter (DAT) using the monoclonal antibody purified from mouse hybridoma clone 6V-23-23. Lewis Lung Carcinoma Porcine Kidney cells engineered to stably express the rat dopamine transporter were fixed by standard methods and stained for DAT using the monoclonal antibody from clone 6V-23-23 and FITC-conjugated secondary antibody. Staining is negligible in cells treated without primary antibody (not shown).
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SLC6A3 / Dopamine Transporter Mouse anti-Rat Monoclonal (6V-23-23) Antibody
Mouse, Rat
ICC, IF, WB
Unconjugated
0.1 ml/$482
SLC6A3 / Dopamine Transporter Antibody
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$423
SLC6A3 / Dopamine Transporter Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using SLC6A3 Polyclonal Antibody at dilution of 1:50.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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SLC6A3 / Dopamine Transporter Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$357
Select
SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
SLC6A3 / Dopamine Transporter Antibody - Western blot analysis of SLC6A3 expression in HEK293 cells. The lane on the left is treated with the antigen-specific peptide.
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SLC6A3 / Dopamine Transporter Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).