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Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
Gene Name: | solute carrier family 6 (neutral amino acid transporter), member 15 |
Family/Subfamily: | Transporter , Neurotransmitter:sodium symporter |
Synonyms: | SLC6A15, Orphan transporter v7-3, Transporter v7-3, NTT73, SBAT1, B0AT2, Hv7-3, V7-3 |
Target Sequences: | NM_018057 NP_060527.2 Q9H2J7 |
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