Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SLC5A5 / NIS is a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.
|Gene Name:||solute carrier family 5 (sodium/iodide cotransporter), member 5|
|Family/Subfamily:||Transporter , Solute:sodium symporter|
|Synonyms:||SLC5A5, Sodium-iodide symporter, Na(+)/I(-) cotransporter, NIS, Sodium/iodide cotransporter, Na(+)/I(-) symporter, Na+/I- symporter, TDH1|
|Target Sequences:||NM_000453 NP_000444.1 Q92911|
If you do not find the reagent or information you require, please contact firstname.lastname@example.org to inquire about additional products in development.