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SLC4A3 / AE3

solute carrier family 4 (anion exchanger), member 3

Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl-/HCO3- exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl-.

Gene Name: solute carrier family 4 (anion exchanger), member 3
Family/Subfamily: Transporter , Anion exchanger
Synonyms: SLC4A3, AE 3, Anion exchange protein 3, Anion exchanger 3, neuronal, Anion exchanger isoform 3, AE3, Neuronal band 3-like protein, Anion exchanger 3, SLC2C, CAE3/BAE3
Target Sequences: NM_005070 NP_005061.2 P48751

Publications (2)

1
Sasanquasaponin induces increase of Cl-/HCO3- exchange of anion exchanger 3 and promotes intracellular Cl- efflux in hypoxia/reoxygenation cardiomyocytes. Qiu LY, Duan GL, Yan YF, Li YY, Wang H, Xiao L, Liao ZP, Chen HP. Molecular medicine reports. 2017 16:2953-2961. (WB; Rat) [Full Text Article] [PubMed:28677776] Related Antibodies: LS-C20639.
2
Suppression of mammalian bone growth by membrane transport inhibitors. Mohamad Y Loqman, Peter G Bush, Colin Farquharson, Andrew C Hall. Journal of cellular biochemistry. 2013 March;114:658-68. [Full Text Article] [PubMed:23059814] Related Antibodies: LS-C20639.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).