Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration (By similarity). Involved in borate homeostasis. In the absence of borate, it functions as a Na+ and OH-(H+) channel. In the presence of borate functions as an electrogenic Na+ coupled borate cotransporter.
Gene Name: | solute carrier family 4, sodium borate transporter, member 11 |
Family/Subfamily: | Transporter , Anion exchanger |
Synonyms: | SLC4A11, CDPD1, CHED2, FECD4, DJ794I6.2, Sodium borate cotransporter 1, BTR1, CDPD, NABC1 |
Target Sequences: | NM_032034 NP_114423.1 Q8NBS3 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.