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SLC30A8 / ZNT8

solute carrier family 30 (zinc transporter), member 8

SLC30A8 / ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.

Gene Name: solute carrier family 30 (zinc transporter), member 8
Family/Subfamily: Transporter , Cation diffusion facilitator
Synonyms: SLC30A8, ZNT8, Zinc transporter 8, Zinc transporter ZnT-8, ZnT-8
Target Sequences: NM_001172811 NP_001166282.1 Q8IWU4

Publications (1)

1
Presence of diabetes autoantigens in extracellular vesicles derived from human islets. Hasilo CP, Negi S, Allaeys I, Cloutier N, Rutman AK, Gasparrini M, Bonneil É, Thibault P, Boilard É, Paraskevas S. Scientific reports. 2017 7:5000. (ICC, WB, Flo; Human, Hamster) [Full Text Article] [PubMed:28694505] [PMC:PMC5504025] Related Antibodies: LS-C303154.

☰ Filters
Antibodies (27)
ELISA Kits (6)
Proteins (5)
Custom (3)
Over-Expression Lysate (2)
Primary (27)
Recombinant (3)
Sandwich (3)
SLC30A8 / ZNT8 (38)
Human (31)
Mouse (2)
Rat (2)
Bat (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (3)
IHC (3)
WB (23)
ELISA (8)
ICC (1)
IF (4)
IP (1)
Peptide-ELISA (2)
rabbit (27)
IgG (11)
polyclonal pc (27)
96-Well Strip Plate (6)
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (12)
aa263-369 (8)
aa107-156 (4)
aa1-80 (3)
140-220 aa, Internal (1)
aa171-220 (1)
No (37)
Yes (1)
Cell Lysates (2)
Plasma (2)
Serum (1)
Tissue Homogenates (3)
10His, N-terminus (1)
His, N-Terminal (2)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Purified (2)
SLC30A8 / ZNT8 Antibody - Western blot of recombinant SLC30A8 / ZNT8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa263-369) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SLC30A8 / ZNT8 Antibody - Western blot of recombinant SLC30A8 / ZNT8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa263-369) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
SLC30A8 / ZNT8 Antibody - Western blot of recombinant SLC30A8 / ZNT8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa263-369) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
SLC30A8 / ZNT8 Antibody - Western blot of recombinant SLC30A8 / ZNT8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa263-369) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
SLC30A8 / ZNT8 Antibody - Western blot of recombinant SLC30A8 / ZNT8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa1-80) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561
SLC30A8 / ZNT8 Antibody - Western blot of recombinant SLC30A8 / ZNT8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa1-80) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596
SLC30A8 / ZNT8 Antibody - Western blot of recombinant SLC30A8 / ZNT8.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa1-80) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755
SLC30A8 / ZNT8 Antibody - SLC30A8 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
WB
Unconjugated
100 µl/$424
SLC30A8 / ZNT8 Protein - Recombinant Solute Carrier Family 30 Member 8 By SDS-PAGE
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E. coli
His, N-Terminal
13.3 kDa
10 µg/$339; 50 µg/$802; 100 µg/$1,214; 200 µg/$1,430; 500 µg/$2,223; 5 mg/$5,601; 2 mg/$2,988
SLC30A8 / ZNT8 Protein - Recombinant Solute Carrier Family 30 Member 8 By SDS-PAGE
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E. coli
His, N-Terminal
10.7 kDa
10 µg/$274; 50 µg/$400; 100 µg/$637; 200 µg/$797; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053
SLC30A8 / ZNT8 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$579
SLC30A8 / ZNT8 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using SLC30A8 Antibody at dilution of 1:100
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
SLC30A8 / ZNT8 Antibody - Immunohistochemistry of SLC30A8 in human pancreas tissue with SLC30A8 Antibody at 5 µg/mL.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
Select
E. coli
10His, N-terminus
43.6 kDa
100 µg/$1,801; 20 µg/$1,247
SLC30A8 / ZNT8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.6 kDa
100 µg/$494
SLC30A8 / ZNT8 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
SLC30A8 / ZNT8 Antibody - Western blot of ZnT-8 antibody
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (140-220 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SLC30A8 / ZNT8 Antibody - Western blot analysis of lysates from K562 cells, using SLC30A8 Antibody. The lane on the right is blocked with the synthesized peptide.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SLC30A8 / ZNT8 Antibody - Western blot analysis of extracts of various cell lines, using SLC30A8 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SLC30A8 / ZNT8 Antibody - Western blot analysis of ZNT8 expression in H9C2 (A), K562 (B) whole cell lysates.
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SLC30A8 / ZNT8 Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Viewing 1-25 of 38 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).