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SLC2A5 / GLUT5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A5/GLUT5 belongs to a family of glucose/fructose transport proteins that exhibit 45-65% amino acid homology. GLUT 5 functions mainly as a fructose transporter and is thought to be largely responsible for the uptake of fructose from the lumen of the small intestine. Its' expression is induced in mice exposed to high fructose diets. GLUT5 is also responsible for the uptake of fructose by spermatozoa. The expression pattern of GLUT5 in maturing spermatids suggests that it may serve as a marker for maturation. Expression of GLUT5 in skeletal muscle is localized to the plasma membrane where it is involved in regulating hexose transfer across the sarcolemma.
| Gene Name: | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| Family/Subfamily: | Transporter , Sugar transporter |
| Synonyms: | SLC2A5, Fructose transporter, Glucose transporter 5, GLUT-5, GLUT5 |
| Target Sequences: | NM_003039 NP_003030.1 P22732 |
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