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SLC2A4 / GLUT-4

solute carrier family 2 (facilitated glucose transporter), member 4

SLC2A4 / GLUT-4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

Gene Name: solute carrier family 2 (facilitated glucose transporter), member 4
Family/Subfamily: Transporter , Sugar transporter
Synonyms: SLC2A4, Glucose transporter 4, Glucose transporter GLUT4, GLUT4, GLUT-4
Target Sequences: NM_001042 NP_001033.1 P14672

Publications (1)

1
Adiponectin stimulates glucose uptake in mouse blastocysts and embryonic carcinoma cells. J Burkuš, A Navarrete Santos, M Schindler, J Babelová, J S Jung, A Špirková, M Kšinanová, V Kovaríková, B Fischer, J Koppel, D Fabian, Š Cikoš. Reproduction (Cambridge, England). 2020 March;159:227-239. [Full Text Article] [PubMed:32023207] Related Antibodies: LS-C143467.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).