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SLC29A1 / ENT1

solute carrier family 29 (equilibrative nucleoside transporter), member 1

SLC29A1 / ENT1 is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene Name: solute carrier family 29 (equilibrative nucleoside transporter), member 1
Family/Subfamily: Transporter , Equilibrative nucleoside transporter
Synonyms: SLC29A1, ENT1, HENT1
Target Sequences: NM_004955 NP_004946.1 Q99808

Publications (4)

1
Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nrnberg B, Haase VH, X. The Journal of clinical investigation. 2012 122:693-710. [PubMed:22269324] [PMC:PMC3266792] Related Antibodies: LS-C96639.
2
Levels of human equilibrative nucleoside transporter-1 are higher in proliferating regions of A549 tumor cells grown as tumor xenografts in vivo. Plotnik DA, Asher C, Chu SK, Miyaoka RS, Garwin GG, Johnson BW, Li T, Krohn KA, Schwartz JL. Nuclear medicine and biology. 2012 39:1161-6. (IHC; Human) [Full Text Article] [PubMed:22985987] [PMC:PMC3478396] Related Antibodies: LS-B3385.
3
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R. Nature. 2015 527:525-530. (IHC; Mouse) [Full Text Article] [PubMed:26560028] [PMC:PMC4849281] Related Antibodies: LS-B3385.
4
The combination of everolimus and zoledronic acid increase the efficacy of gemcitabine in a mouse model of pancreatic adenocarcinoma. Vitellius C, Fizanne L, Menager-Tabourel E, Nader J, Baize N, Laly M, Lermite E, Bertrais S, Caroli-Bosc FX. Oncotarget. 2018 June;9:28069-28082. [Full Text Article] [PubMed:29963262] [PMC:PMC6021353] Related Antibodies: LS-C178673.
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Antibodies (52)
Primary (52)
SLC29A1 / ENT1 (52)
Human (51)
Mouse (12)
Rat (13)
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IHC (20)
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rabbit (50)
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IgG (39)
polyclonal pc (52)
APC Conjugated (4)
Azide-free (4)
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FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (29)
Ser254 (7)
aa234-263 (7)
aa402-431 (7)
pSer254 (7)
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C-Terminus (1)
N-terminus, aa15-50 (1)
aa15-64 (1)
aa343-393 (1)
aa5-50 (1)
No (49)
Yes (3)
SLC29A1 / ENT1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Goat, Guinea pig, Bovine, Horse, Bat, Human, Monkey
IHC-P
Unconjugated
50 µg/$440
SLC29A1 / ENT1 Antibody - Anti-ENT1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
SLC29A1 / ENT1 Antibody - Anti-ENT1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
SLC29A1 / ENT1 Antibody - Anti-ENT1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
SLC29A1 / ENT1 Antibody - Immunohistochemical of paraffin-embedded H. brain section using ENT1(Slc29a1). Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa402-431) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
SLC29A1 / ENT1 Antibody
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
SLC29A1 / ENT1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
SLC29A1 / ENT1 Antibody - Western blot of ENT1 antibody
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (N-terminus, aa15-50) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SLC29A1 / ENT1 Antibody - Western blot analysis of lysates from MDA-MB-435 cells, using ENT1 antibody.
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa15-64) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa402-431) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
SLC29A1 / ENT1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer tissue using SLC29A1 Antibody at dilution of 1:100
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
SLC29A1 / ENT1 Antibody - Testis, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (Ser254) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa234-263) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa234-263) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa234-263) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa234-263) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa234-263) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (aa234-263) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
SLC29A1 / ENT1 Antibody - Immunohistochemistry of paraffin-embedded rat brain using SLC29A1 antibody at dilution of 1:100 (40x lens).
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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SLC29A1 / ENT1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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SLC29A1 / ENT1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (Ser254) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal (pSer254) Antibody
Human
DB, ELISA
Unconjugated
200 µl/$734
SLC29A1 / ENT1 Antibody - Western blot analysis of ENT1 using Jurkat whole cells lysates
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SLC29A1 / ENT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).