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SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine.
| Gene Name: | solute carrier family 28 (concentrative nucleoside transporter), member 3 |
| Family/Subfamily: | Transporter , Nucleoside:sodium symporter |
| Synonyms: | SLC28A3, CNT3, HCNT3, CNT 3 |
| Target Sequences: | NM_022127 NP_071410.1 Q9HAS3 |
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