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SLC25A27 / UCP4

solute carrier family 25, member 27

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.

Gene Name: solute carrier family 25, member 27
Family/Subfamily: Transporter , Mitochondrial carrier
Synonyms: SLC25A27, RP11-446F17.2, UCP 4, UCP4, Uncoupling protein 4
Target Sequences: NM_004277 NP_004268.3 O95847

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
SLC25A27 / UCP4 (4)
No (4)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
SLC25A27 / UCP4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.9 kDa
20 µg/$150
SLC25A27 / UCP4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.9 kDa
100 µg/$494
SLC25A27 / UCP4 Protein
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E. coli
His, N-Terminal
35.9 kDa
50 µg/$419
SLC25A27 / UCP4 Protein - 12.5% SDS-PAGE of human SLC25A27 stained with Coomassie Blue
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Wheat Germ Extract
GST
52.69 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).