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SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
SLC25A25 belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene.
| Gene Name: | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 |
| Synonyms: | SLC25A25, APC3, MCSC, PCSCL, Phosphate carrier), member 25, KIAA1896, SCAMC-2, RP11-395P17.4, SCAMC2, MCSC3 |
| Target Sequences: | NM_052901 NP_443133.2 Q6KCM7 |
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