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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
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SLC25A20 / CACT
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC25A20 / CACT is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
| Gene Name: | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| Family/Subfamily: | Transporter , Mitochondrial carrier |
| Synonyms: | SLC25A20, CACT, CAC |
| Target Sequences: | NM_000387 NP_000378.1 O43772 |
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