SLC22A6 / OAT1

solute carrier family 22 (organic anion transporter), member 6

Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

SLC22A6 / OAT1 (5)

Publications

No (5)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human SLC22A6 / OAT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86799

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.6 kDa

Price:

20 µg/$215

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Human SLC22A6 / OAT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86800

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.1 kDa

Price:

20 µg/$150

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SLC22A6 / OAT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105829

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.1 kDa

Price:

100 µg/$494

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Human SLC22A6 / OAT1 Protein (Recombinant GST, N-terminus) (aa451-550) - LS-G61088

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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SLC22A6 / OAT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100392

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.6 kDa

Price:

100 µg/$710

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