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Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET).
Gene Name: | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
Family/Subfamily: | Transporter , Organic cation transporter |
Synonyms: | SLC22A4, ETT, Ergothioneine transporter, ET transporter, OCTN1, UT2H |
Target Sequences: | NM_003059 NP_003050.2 Q9H015 |
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