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SLC22A18

solute carrier family 22, member 18

SLC22A18 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Two alternatively spliced transcript variants encoding the same protein have been described.

Gene Name: solute carrier family 22, member 18
Family/Subfamily: Transporter , Organic cation transporter
Synonyms: SLC22A18, BWR1A, BWSCR1A, HET, ORCTL2, ITM, p45-BWR1A, TSSC5, IMPT1, ORCTL-2, SLC22A1L
Target Sequences: NM_002555 NP_002546.3 Q96BI1

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Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
SLC22A18 (6)
No (6)
GST (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
SLC22A18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
44.7 kDa
20 µg/$150
SLC22A18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
44.7 kDa
100 µg/$710
SLC22A18 Protein - 12.5% SDS-PAGE of human SLC22A18 stained with Coomassie Blue
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Wheat Germ Extract
GST
71.2 kDa
2 µg/$439
SLC22A18 Protein - Purified recombinant protein SLC22A18 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
44.7 kDa
20 µg/$1,107
SLC22A18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
44.7 kDa
20 µg/$215
SLC22A18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
44.7 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).