SLC22A17

solute carrier family 22, member 17

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

SLC22A17 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human SLC22A17 Protein (Recombinant GST) (Full Length) - LS-G33720

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.7 kDa

Price:

2 µg/$439

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SLC22A17 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112537

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.5 kDa

Price:

100 µg/$710

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Human SLC22A17 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82928

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.5 kDa

Price:

20 µg/$215

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