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SLC22A16
solute carrier family 22 (organic cation/carnitine transporter), member 16
High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent.
| Gene Name: | solute carrier family 22 (organic cation/carnitine transporter), member 16 |
| Family/Subfamily: | Transporter , Organic cation transporter |
| Synonyms: | SLC22A16, Carnitine transporter 2, CT2, Flipt 2, FLIPT2, OKB1, OCT6, WUGSC:RG331P03.1, DJ261K5.1, OAT6, Organic cation transporter 6 |
| Target Sequences: | NM_033125 NP_149116.2 Q86VW1 |
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