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SLC1A3 / EAAT1

solute carrier family 1 (glial high affinity glutamate transporter), member 3

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

Gene Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Family/Subfamily: Transporter , Sodium:dicarboxylate symporter
Synonyms: SLC1A3, EA6, EAAT-1, EAAT1, GLAST, GLAST1, GLAST-1
Target Sequences: NM_004172 NP_004163.3 P43003

Publications (2)

1
Quantitative proteomic analysis of the brainstem following lethal sarin exposure. Meade ML, Hoffmann A, Makley MK, Snider TH, Schlager JJ, Gearhart JM. Brain research. 2015 1611:101-13. (WB; Guinea pig) [Full Text Article] [PubMed:25842371] Related Antibodies: LS-A9447.
2
Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs. Daisuke Ukeba, Hideki Sudo, Takeru Tsujimoto, Katsuro Ura, Katsuhisa Yamada, Norimasa Iwasaki. EBioMedicine. 2020 March;53:102698. [Full Text Article] [PubMed:32143180] [PMC:PMC7057222]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).