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SLC17A5

solute carrier family 17 (acidic sugar transporter), member 5

Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential-dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO3-/H+ cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed and secreted in saliva.

Gene Name: solute carrier family 17 (acidic sugar transporter), member 5
Family/Subfamily: Transporter , Lysosomal sialate transporter
Synonyms: SLC17A5, AST, Membrane glycoprotein HP59, SD, Sialin, SIASD, NSD, Sialic acid storage disease, SLD, ISSD
Target Sequences: NM_012434 NP_036566.1 Q9NRA2

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Proteins (1)
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SLC17A5 (1)
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SLC17A5 Protein - Recombinant Anion/Sugar Transporter By SDS-PAGE
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E. coli
His-T7
33.0 kDa
10 µg/$290; 50 µg/$497; 100 µg/$795; 200 µg/$992; 1 mg/$2,134; 500 µg/$1,658; 5 mg/$3,969
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).