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SLC16A1 / MCT1

solute carrier family 16 (monocarboxylate transporter), member 1

Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

Gene Name: solute carrier family 16 (monocarboxylate transporter), member 1
Family/Subfamily: Transporter , Monocarboxylic acid transporter
Synonyms: SLC16A1, MCT1, MCT, HHF7, Monocarboxylate transporter 1, MCT 1
Target Sequences: NM_003051 NP_003042.3 P53985

Publications (1)

1
Label-free sensing of exosomal MCT1 and CD147 for tracking metabolic reprogramming and malignant progression in glioma. A Thakur, G Qiu, C Xu, X Han, T Yang, S P Ng, K W Y Chan, C M L Wu, Y Lee. Science advances. 2020 June;6:eaaz6119. [Full Text Article] [PubMed:32637597] [PMC:PMC7319757]

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ELISA Kits (8)
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SLC16A1 / MCT1 (8)
Human (2)
Mouse (2)
Rat (3)
96-Well Strip Plate (8)
No (7)
Yes (1)
Cell Lysates (1)
Plasma (4)
Serum (4)
Tissue Homogenates (3)
SLC16A1 / MCT1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$834
SLC16A1 / MCT1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SLC16A1 / MCT1 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
SLC16A1 / MCT1 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
SLC16A1 / MCT1 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
SLC16A1 / MCT1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SLC16A1 / MCT1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SLC16A1 / MCT1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$893
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).