SLC12A1 / NKCC2

solute carrier family 12 (sodium/potassium/chloride transporter), member 1

SLC12A1 / NKCC2 is a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

☰ Filters

Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

SLC12A1 / NKCC2 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His-S (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

SLC12A1 / NKCC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123252

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121.3 kDa

Price:

100 µg/$710

Select

Human SLC12A1 / NKCC2 Protein (Recombinant GST, N-terminus) (aa80-172) - LS-G60125

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human SLC12A1 / NKCC2 Protein (Recombinant GST) (Full Length) - LS-G30447

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.9 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human SLC12A1 / NKCC2 Protein (Recombinant His-S) (aa814-1099) - LS-G25466

Source:

E. coli

Tag:

His-S

Molecular Weight:

36.8 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

Select

Human SLC12A1 / NKCC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81656

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121.3 kDa

Price:

20 µg/$215

Viewing 1-5 of 5 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.