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SLBP

stem-loop binding protein

RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs.

Gene Name: stem-loop binding protein
Synonyms: SLBP, HBP, Stem-loop binding protein, Histone binding protein
Target Sequences: NM_006527 NP_006518.1 Q14493

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
SLBP (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
SLBP Protein - Purified recombinant protein SLBP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
31.1 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
31.1 kDa
20 µg/$150
SLBP Protein - 12.5% SDS-PAGE of human SLBP stained with Coomassie Blue
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Wheat Germ Extract
GST
55.44 kDa
10 µg/$479; 25 µg/$670
SLBP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.1 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).