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SLA

Src-like-adaptor

Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.

Gene Name: Src-like-adaptor
Family/Subfamily: Protein Kinase Non Catalytic , not assigned-Protein Kinase Non Catalytic
Synonyms: SLA, SLA1, SLAP, Src-like-adapter, Src-like-adapter protein 1, SLAP-1, HSLAP, SLAP1, Src-like-adaptor
Target Sequences: NM_001045556 NP_006739.2 Q13239

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).