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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.
TCR Screening ServicesTest your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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SLA
Src-like-adaptor
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
| Gene Name: | Src-like-adaptor |
| Family/Subfamily: | Protein Kinase Non Catalytic , not assigned-Protein Kinase Non Catalytic |
| Synonyms: | SLA, SLA1, SLAP, Src-like-adapter, Src-like-adapter protein 1, SLAP-1, HSLAP, SLAP1, Src-like-adaptor |
| Target Sequences: | NM_001045556 NP_006739.2 Q13239 |
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