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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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SKP2

S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms.

Gene Name: S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Synonyms: SKP2, F-box/LRR-repeat protein 1, FBL1, FLB1, F-box protein Skp2, FBXL1, p45, p45skp2
Target Sequences: NM_005983 NP_005974.2 Q13309

Viewing 1-25 of 63 items
SKP2 Antibody - Anti-SKP2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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(1) Publication(s)
Mouse Monoclonal (IgG1,k) to Human SKP2
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50µg   0.5mg/ml   $485.00
SKP2 Antibody - Anti-SKP2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal to Human SKP2
Human
IHC, IHC-P
Unconjugated
250µl   0.2mg/ml   $425.00
SKP2 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human SKP2
Human
IHC, IHC-P, IP, WB
Unconjugated
50µl   1mg/ml   $425.00
SKP2 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SKP2/p45 Antibody. The picture on the right is blocked with the synthesized peptide.
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Rabbit Polyclonal (IgG) to Human SKP2
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
SKP2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human SKP2
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100µg   1mg/ml   $295.00
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IP, WB
Unconjugated
100µg   $635.00
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IP, WB
HRP Conjugated
100µl   $800.00
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IP, WB
Biotin Conjugated
100µl   $800.00
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IP, WB
FITC Conjugated
100µl   $800.00
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IP, WB
PE Conjugated
100µl   $800.00
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IP, WB
AP Conjugated
100µl   $800.00
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IP, WB
APC Conjugated
100µl   $800.00
SKP2 Antibody - Immunohistochemical analysis of SKP2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human SKP2
Bovine, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
SKP2 Antibody
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Rabbit Polyclonal (IgG) to Human SKP2
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
SKP2 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using SKP2/p45 antibody.
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   100µl   1µg/µl   $305.00
SKP2 Antibody - Western blot of 293 cell lysate using SKP2/p45 Antibody
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Rabbit Polyclonal to Human SKP2
Human
ICC, IF, IHC, WB
Unconjugated
100µg   $305.00
SKP2 Antibody - Western blot of Skp2 p45 antibody
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
SKP2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
SKP2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50µg   $285.00; 100µg   $385.00
SKP2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
SKP2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human SKP2
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50µg   $285.00; 100µg   $385.00
SKP2 Antibody - Immunohistochemistry of paraffin-embedded mouse liver using SKP2 antibodyat dilution of 1:100 (40x lens).
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Rabbit Polyclonal (IgG) to Human SKP2
Mouse, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human SKP2
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100µg   $530.00
SKP2 Antibody - IHC of SKP2/p45 (P399) pAb in paraffin-embedded human lung carcinoma tissue.
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Rabbit Polyclonal to Human SKP2
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
Select
Mouse Monoclonal [clone SKP2-8D9] (IgG1) to Human SKP2
Human
Flo, IHC, IHC-P
Unconjugated, Concentrated
100µg   $665.00

Viewing 1-25 of 63 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).