SKD1 / VPS4B

vacuolar protein sorting 4 homolog B (S. cerevisiae)

Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

SKD1 / VPS4B (5)

Publications

No (5)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human SKD1 / VPS4B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89314

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.1 kDa

Price:

20 µg/$150

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Human SKD1 / VPS4B Protein (Recombinant GST) (Full Length) - LS-G31677

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.58 kDa

Price:

10 µg/$479; 25 µg/$670

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SKD1 / VPS4B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100404

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.1 kDa

Price:

100 µg/$494

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Human SKD1 / VPS4B Protein (Recombinant His) - LS-G2571

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human SKD1 / VPS4B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71255

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.1 kDa

Price:

20 µg/$1,107

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