LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

SIX1

SIX homeobox 1

Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2 (By similarity). Regulates the expression of CCNA1.

Gene Name: SIX homeobox 1
Synonyms: SIX1, BOS3, DFNA23, Sine oculis homeobox homolog 1, SIX homeobox 1, TIP39, Homeobox protein SIX1
Target Sequences: NM_005982 NP_005973.1 Q15475

Filtered By: None
Target
six1 (22)
Reactivity
Human (21)
Mouse (8)
Rat (5)
Bat (4)
Bovine (4)
Chimpanzee (6)
Dog (4)
Gibbon (3)
Guinea pig (4)
Hamster (4)
Horse (4)
Monkey (4)
Pig (8)
Sheep (4)
Application
IHC (1)
WB (17)
ELISA (9)
Host
rabbit (20)
mouse (2)
Isotype
IgG (13)
IgG1 (1)
IgG2a,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (20)
Clone
1H4 (1)
3C7 (1)
Format
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (13)
Epitope
C-Terminus (8)
aa111-160 (1)
aa245-282 (1)
aa252-266 (1)
aa69-102 (1)
aa80-160 (1)
Publications
No (22)
Showing 1-22 out of 22 results
Anti-SIX1 Antibody LS-C500844

Rabbit Polyclonal (IgG) to Human SIX1
Rat, Human
ELISA IHC WB
Unconjugated
Anti-SIX1 Antibody (HRP) LS-C500849

Rabbit Polyclonal (IgG) to Human SIX1
Human
ELISA
HRP Conjugated
Anti-SIX1 Antibody (Biotin) LS-C500847

Rabbit Polyclonal (IgG) to Human SIX1
Human
ELISA
Biotin Conjugated
Anti-SIX1 Antibody (FITC) LS-C500851

Rabbit Polyclonal (IgG) to Human SIX1
Human
ELISA
FITC Conjugated
Anti-SIX1 Antibody (aa80-160) LS-C386067

Rabbit Polyclonal (IgG) to Human SIX1
Mouse, Human
ELISA WB
Unconjugated
Anti-SIX1 Antibody (aa111-160) LS-C291338

Rabbit Polyclonal (IgG) to Human SIX1
Mouse, Human
ELISA WB
Unconjugated
Anti-SIX1 Antibody (aa252-266) LS-C10188

Rabbit Polyclonal (IgG) to Human SIX1
Human
ELISA WB
Unconjugated
Anti-SIX1 Antibody (aa69-102) LS-C392817

Rabbit Polyclonal to Human SIX1
Mouse, Human
ELISA WB
Unconjugated
Anti-SIX1 Antibody (clone 3C7) LS-C198200

Mouse Monoclonal [clone 3C7] (IgG2a,k) to Human SIX1
Human
ELISA
Unconjugated
Anti-SIX1 Antibody (clone 1H4) LS-C173609

Mouse Monoclonal [clone 1H4] (IgG1) to Human SIX1
Human
WB
Unconjugated
Anti-SIX1 Antibody LS-C139037

Rabbit Polyclonal to Mouse SIX1
Unconjugated
Anti-SIX1 Antibody (C-Terminus) LS-C101389

Rabbit Polyclonal (IgG) to Human SIX1
Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
Anti-SIX1 Antibody (C-Terminus, HRP) LS-C427779

Rabbit Polyclonal (IgG) to Human SIX1
Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
Anti-SIX1 Antibody (C-Terminus, Biotin) LS-C427777

Rabbit Polyclonal (IgG) to Human SIX1
Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
Anti-SIX1 Antibody (C-Terminus, FITC) LS-C427778

Rabbit Polyclonal (IgG) to Human SIX1
Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
Anti-SIX1 Antibody (aa245-282) LS-C408101

Rabbit Polyclonal to Human SIX1
Human
WB
Unconjugated
Anti-SIX1 Antibody (C-Terminus) LS-C110311

Rabbit Polyclonal to Human SIX1
Pig, Human
WB
Unconjugated
Anti-SIX1 Antibody (C-Terminus, HRP) LS-C437424

Rabbit Polyclonal to Human SIX1
Pig, Human, Chimpanzee
WB
HRP Conjugated
Anti-SIX1 Antibody (C-Terminus, Biotin) LS-C437422

Rabbit Polyclonal to Human SIX1
Pig, Human, Chimpanzee
WB
Biotin Conjugated
Anti-SIX1 Antibody (C-Terminus, FITC) LS-C437423

Rabbit Polyclonal to Human SIX1
Pig, Human, Chimpanzee
WB
FITC Conjugated
Anti-SIX1 Antibody LS-C490560

Rabbit Polyclonal (IgG) to Human SIX1
Human
WB
Unconjugated
Anti-SIX1 Antibody LS-C410185

Rabbit Polyclonal (IgG) to Human SIX1
Mouse, Human
WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number